Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvellous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich nightlife and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities in the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Spain, Cannes & Italy

7 Nights

MSC Seaview

Wednesday, 1 May 2024

Rome (Civitavecchia)

Twin From $5,447 pp

Quad From $4,171 pp

Luxury Large Ship Cruises

Italy, Spain & Marseille

7 Nights

MSC Seaside

Sunday, 5 May 2024

Rome (Civitavecchia)

Twin From $5,029 pp

Quad From $3,948 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Fantasia

Tuesday, 7 May 2024

Rome (Civitavecchia)

Twin From $1,596 pp

Quad From $1,513 pp

Luxury Large Ship Cruises

Spain, Cannes & Italy

7 Nights

MSC Seaview

Wednesday, 8 May 2024

Rome (Civitavecchia)

Twin From $1,537 pp

Quad From $1,896 pp

Luxury Large Ship Cruises

Greece, Malta and Italy

10 Nights

Norwegian Epic

Thursday, 9 May 2024

Rome (Civitavecchia)

Twin From $2,067 pp

Quad From $3,021 pp

Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
Amazing Included Value

Italy & Spain

7 Nights

Oasis Of The Seas

Thursday, 9 May 2024

Rome (Civitavecchia)

Twin From $2,457 pp

Quad From $1,835 pp

Amazing Included Value

Rome to Naples

6 Nights

MSC Divina

Friday, 10 May 2024

Rome (Civitavecchia)

Twin From $1,200 pp

Quad From $1,185 pp

Luxury Large Ship Cruises

Greece, Izmir & Naples

7 Nights

MSC Divina

Friday, 10 May 2024

Rome (Civitavecchia)

Twin From $1,799 pp

Quad From $1,833 pp

Luxury Large Ship Cruises

Italy, Spain & Marseille

7 Nights

MSC Seaside

Sunday, 12 May 2024

Rome (Civitavecchia)

Twin From $1,654 pp

Quad From $2,202 pp

Luxury Large Ship Cruises

Italy, Croatia & Montenegro

11 Nights

Celebrity Constellation

Monday, 13 May 2024

Rome (Civitavecchia)

Twin From $2,216 pp

Quad From $1,279 pp

Premium Cruise Line

Greece & Turkey

14 Nights

Queen Victoria

Monday, 13 May 2024

Rome (Civitavecchia)

Twin From $3,491 pp

Triple From $3,194 pp

Cunard Sale  Cunard Sale
Premium Cruise Line

Rome (Civitavecchia) to Istanbul

7 Nights

Queen Victoria

Monday, 13 May 2024

Rome (Civitavecchia)

Twin From $1,648 pp

Single From $2,884 pp

Cunard Sale  Cunard Sale
Premium Cruise Line

Italy, France & Spain

7 Nights

MSC Fantasia

Tuesday, 14 May 2024

Rome (Civitavecchia)

Twin From $1,460 pp

Quad From $1,518 pp

Luxury Large Ship Cruises

Spain, Cannes & Italy

7 Nights

MSC Seaview

Wednesday, 15 May 2024

Rome (Civitavecchia)

Twin From $1,615 pp

Quad From $1,518 pp

Luxury Large Ship Cruises

France, Italy & Spain

7 Nights

Oasis Of The Seas

Thursday, 16 May 2024

Rome (Civitavecchia)

Twin From $2,215 pp

Quad From $1,566 pp

Amazing Included Value

Greece, Izmir & Naples

7 Nights

MSC Divina

Friday, 17 May 2024

Rome (Civitavecchia)

Twin From $1,828 pp

Quad From $1,717 pp

Luxury Large Ship Cruises

Italy, Greece & Kusadasi (Ephesus)

9 Nights

Odyssey Of The Seas

Friday, 17 May 2024

Rome (Civitavecchia)

Twin From $3,491 pp

Quad From $2,463 pp

Amazing Included Value

Rome (Civitavecchia) to Piraeus (Athens)

7 Nights

Sun Princess

Saturday, 18 May 2024

Rome (Civitavecchia)

Twin From $3,481 pp

Quad From $2,415 pp

Italy, Spain & Marseille

7 Nights

MSC Seaside

Sunday, 19 May 2024

Rome (Civitavecchia)

Twin From $1,693 pp

Quad From $1,959 pp

Luxury Large Ship Cruises

Greece, Malta and Italy

10 Nights

Norwegian Epic

Sunday, 19 May 2024

Rome (Civitavecchia)

Twin From $2,037 pp

Quad From $2,991 pp

Drinks, WiFi, Dining Included  Drinks, WiFi, Dining Included
Amazing Included Value