Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvellous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich nightlife and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities in the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Valencia & Cagliari

5 Nights

MSC Lirica

Thursday, 21 November 2024

Rome (Civitavecchia)

Twin From $513 pp

Quad From $799 pp

Luxury Large Ship Cruises

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 25 November 2024

Rome (Civitavecchia)

Twin From $1,120 pp

Quad From $1,484 pp

Luxury Large Ship Cruises

Rome to Marseille

2 Nights

MSC Lirica

Tuesday, 26 November 2024

Rome (Civitavecchia)

Twin From $295 pp

Quad From $290 pp

Rome to Valencia

4 Nights

MSC Lirica

Tuesday, 26 November 2024

Rome (Civitavecchia)

Twin From $591 pp

Triple From $841 pp

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 26 November 2024

Rome (Civitavecchia)

Twin From $761 pp

Quad From $757 pp

Luxury Large Ship Cruises

Rome to Fort Lauderdale

21 Nights

Viking Sky

Thursday, 28 November 2024

Rome (Civitavecchia)

Twin From $12,091 pp

Single From $24,182 pp

Rome to Miami

16 Nights

Scarlet Lady

Thursday, 28 November 2024

Rome (Civitavecchia)

Twin From $2,879 pp

Single From $5,556 pp

Adult Only Cruise Line

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 2 December 2024

Rome (Civitavecchia)

Twin From $1,353 pp

Quad From $1,392 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 3 December 2024

Rome (Civitavecchia)

Twin From $849 pp

Quad From $1,693 pp

Luxury Large Ship Cruises

Rome to Fort Lauderdale

18 Nights

Island Princess

Wednesday, 4 December 2024

Rome (Civitavecchia)

Twin From $1,572 pp

Single From $2,929 pp

Sale Fare  Sale Fare
Premium Cruise Line

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 9 December 2024

Rome (Civitavecchia)

Twin From $2,187 pp

Quad From $1,921 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 10 December 2024

Rome (Civitavecchia)

Twin From $742 pp

Quad From $766 pp

Luxury Large Ship Cruises

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 16 December 2024

Rome (Civitavecchia)

Twin From $1,654 pp

Single From $19,294 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 17 December 2024

Rome (Civitavecchia)

Twin From $955 pp

Quad From $931 pp

Luxury Large Ship Cruises

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 23 December 2024

Rome (Civitavecchia)

Twin From $1,925 pp

Single From $3,138 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 24 December 2024

Rome (Civitavecchia)

Twin From $1,683 pp

Quad From $2,333 pp

Luxury Large Ship Cruises

Rome (Civitavecchia) to Marseille

3 Nights

MSC Magnifica

Friday, 27 December 2024

Rome (Civitavecchia)

Twin From $1,093 pp

Quad From $1,208 pp

Italy, Marseille & Spain

8 Nights

MSC Magnifica

Friday, 27 December 2024

Rome (Civitavecchia)

Twin From $2,438 pp

Quad From $2,675 pp

Luxury Large Ship Cruises

Italy, Valletta, Barcelona & Marseille

7 Nights

MSC World Europa

Monday, 30 December 2024

Rome (Civitavecchia)

Twin From $2,226 pp

Single From $3,148 pp

Luxury Large Ship Cruises

Italy, France & Spain

7 Nights

MSC Lirica

Tuesday, 31 December 2024

Rome (Civitavecchia)

Twin From $1,867 pp

Quad From $2,537 pp

Luxury Large Ship Cruises